Gallium nitrate

Gallium nitrate
IUPAC name

Gallium trinitrate
Other names

Gallium(III) nitrate
Nitric acid, gallium salt
Identifiers
CAS number 69365-72-6 Y
PubChem 61635
ChEMBL CHEMBL1200983 N
Jmol-3D images Image 1
Properties
Molecular formula Ga(NO3)3
Hazards
EU classification O Xi
R-phrases R8 R36/37/38
S-phrases S17 S26
 N (verify) (what is: Y/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Gallium nitrate (brand name Ganite) is the gallium salt of nitric acid with the chemical formula Ga(NO3)3. It is a drug used to treat symptomatic hypercalcemia secondary to cancer. It works by preventing the breakdown of bone through the inhibition of osteoclast activity, thus lowering the amount of free calcium in the blood.[1][2] Gallium nitrate is also used to synthesize other gallium compounds.

Contents

Preparation

Gallium nitrate is commercially available as the hydrate. The nonahydrate may also be prepared by dissolving gallium in nitric acid, followed by recrystallization.[3] The structure of gallium nitrate nonahydrate has been determined by X-ray crystallography.[4]

See also

References

  1. ^ Gallium Nitrate monograph. Lexi-Comp Online, Lexi-Drugs Online, Lexi-Comp Inc. Hudson, OH. Available at: [1]. Accessed September 13th, 2008.
  2. ^ Ganite at drugs.com
  3. ^ Birnara, Christiana; Kessler, Vadim G.; Papaefstathiou, Giannis S. (2009). "Mononuclear gallium(III) complexes based on salicylaldoximes: Synthesis, structure and spectroscopic characterization". Polyhedron 28 (15): 3291. doi:10.1016/j.poly.2009.04.039. 
  4. ^ Hendsbee, Arthur; Pye, Cory; Masuda, Jason (2009). "Hexaaquagallium(III) trinitrate trihydrate". Acta Crystallographica E 65: i65. doi:10.1107/S1600536809028086. 

External links